10-Formyl-5,8-dideazafolic acid

SKU: orb1687046

Description

This small molecule serves as a substrate for 10-formyltetrahydrofolate dehydrogenase and acts as an inhibitor of thymidylate synthase. It is used in biochemical research to study folate metabolism, nucleotide biosynthesis, and for evaluating potential anticancer strategies in vitro.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 61038-31-1
• MW: 467.43
• Purity: 96.04% (May vary between batches)
• Formula: C₂₂H₂₁N₅O₇
• SMILES: Nc1nc(=O)c2cc(CN(C=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)ccc2[nH]1
• Target: DNA/RNA Synthesis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.14 mM);DMSO:60 mg/mL (128.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNASynthesis, DNA Synthesis, RNASynthesis, RNA Synthesis, Thymidylate Synthase

Compound Identifiers

PubChem CID

135566959