Ion Channel Modulators
Ion channels are proteins that span the cell membrane and control the flow of ions such as sodium, potassium, and calcium into and out of the cell. The activity of ion channels is essential for many cellular processes, such as muscle contraction, nerve impulse conduction, and hormone secretion. Ion channel modulators are small molecules that interact with specific ion channels.
- VX661 [orb181347]
[1152311-62-0]
520.5
C26H27F3N2O6
C(C1=CC=C2OC(F)(F)OC2=C1)(C(NC1C(F)=CC2=C(C=1)C=C(C(C)(C)CO)N2C[C@H](O)CO)=O)1CC1
10 mM * 1 mL in DMSO, 100 mg, 250 mg, 1000 mg - Sodium-Channel-inhibitor-1 [orb181326]
[1198117-23-5]
473.42
C24H19F4N3O3
O=C(C1N(CCC2=NC=CC=C2)C(C3=C1C(F)=CC=C3)=O)NCC4=CC=C(OC(F)(F)F)C=C4
100 mg, 250 mg, 1000 mg - PPQ-102 [orb181305]
[931706-15-9]
438.48
C26H22N4O3
C12N3C(C4=CC=CC=C4)=C4C(=O)N(C)C(=O)N(C)C4=C3C(C3=CC=C(C)O3)NC=1C=CC=C2
10 mM * 1 mL in DMSO, 100 mg, 250 mg, 1000 mg - KU14R [orb181273]
[189224-48-4]
214.26
C13H14N2O
CCC1(C2=NC=CN2)OC3=CC=CC=C3C1
100 mg, 250 mg, 1000 mg - TAK-438 [orb181155]
[1260141-27-2]
461.46
C17H16FN3O2S.C4H4O4
N(S(C1=CC=CN=C1)(=O)=O)1C(C2=CC=CC=C2F)=CC(CNC)=C1.C(O)(=O)/C=C/C(O)=O
100 mg, 250 mg, 1000 mg - Ralfinamide [orb181142]
[202825-45-4]
398.44902
C17H19N2O2F.CH4O3S
C[C@H](NCC1=CC=C(OCC2=CC=CC=C2F)C=C1)C(N)=O.CS(=O)(O)=O
100 mg, 250 mg, 1 g - Rufinamide [orb181120]
[106308-44-5]
238.1935
C10H8F2N4O
NC(=O)C1=CN(N=N1)CC2=C(F)C=CC=C2F
100 mg, 250 mg, 1000 mg - ICILIN [orb181068]
[36945-98-9]
311.2921
C16H13N3O4
O=C1N([H])C(C2C([H])=C([H])C([H])=C(C=2[H])[N+](=O)[O-])=C([H])C([H])([H])N1C1=C([H])C([H])=C([H])C([H])=C1O[H]
100 mg, 250 mg, 1000 mg - IOWH-032 [orb181036]
[1191252-49-9]
545.18
C22H15Br2N3O4
BrC1=C(O)C(Br)=CC(C2=NOC(C(NCC3=CC=C(OC4=CC=CC=C4)C=C3)=O)=N2)=C1
100 mg, 250 mg, 1000 mg - 1 imageCFTRinh 172 [orb180957]
[307510-92-5]
409.4
C18H10F3NO3S2
C(O)(=O)C1=CC=C(/C=C2\SC(=S)N(C3=CC=CC(C(F)(F)F)=C3)C\2=O)C=C1
10 mM * 1 mL in DMSO, 100 mg, 250 mg, 1000 mg -
