Cart summary

You have no items in your shopping cart.

Y-27632 2HCL

Catalog Number: orb154626

DispatchUsually dispatched within 5-10 working days
$ 390.00
Catalog Numberorb154626
CategorySmall Molecules
DescriptionY-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM.
CAS Number[129830-38-2]
MW320.26
SMILESC[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
FormulaC14H23Cl2N3O
Hazard InformationNon-Toxic
StorageCan be stored for 2 years at -20°C in powder form, 2 weeks at 4°C in DMSO, and 6 months at -80°C in DMSO.
NoteFor research use only
Expiration Date12 months from date of receipt.

Filter by Applications

Filter by Reactivity

Barbora Schwarzova, Tim Studemann, Muhammed Sonmez, Judith Rossinger, Bangfen Pan, Thomas Eschenhagen, Justus Stenzig, J. Simon Wiegert, Torsten Christ & Florian Weinberger Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES Pflugers Arch., (2023)

Applications

Cell Culture

Reactivity

Human

Karl T Wagner 1, Rick X Z Lu 1, Shira Landau 1, Sarah A Shawky 2, Yimu Zhao 1, David F Bodenstein 1, Luis Felipe Jiménez Vargas 1, Richard Jiang 3, Sargol Okhovatian 1, Ying Wang 1, Chuan Liu 1, Daniel Vosoughi 4, Dakota Gustafson 4, Jason E Fish 5, Carolyn L Cummins 6, Milica Radisic 1 Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues Biofabrication, (2024)

J Raabe, I Wittig, P Laurette, K Stathopoulou, T Brand Physioxia rewires mitochondrial complex composition to protect stem cell viability Redox Biology, (2024)

Mireia Nàger 1, Kenneth B Larsen 2 3, Zambarlal Bhujabal 2, Trine B Kalstad 2, Judith Rössinger 4, Truls Myrmel 1 2, Florian Weinberger 4 5, Asa B Birgisdottir Mitophagy is induced in human engineered heart tissue after simulated ischemia and reperfusion J Cell Sci ., (2025)

Y-27632 2HCL

Chemical structure of Y-27632 2HCL.

Y-27632 2HCL

Y-27632 2HCL

  • Y 27632 [orb1713679]

    ≥98% (HPLC)

    146986-50-7

    320.3

    C14H23Cl2N3O

    1 mg
  • Y 27632 [orb1713678]

    ≥98% (HPLC)

    146986-50-7

    320.3

    C14H23Cl2N3O

    5 mg