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CD163 antibody
Catalog Number: orb13303
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| Product Name | CD163 antibody |
|---|---|
| Catalog Number | orb13303 |
| Species/Host | Rabbit |
| Reactivity | Guinea pig, Human, Mouse, Rat |
| Conjugation | Unconjugated |
| Custom conjugations | |
| Tested applications | ICC, IF, IHC-P, WB |
| Immunogen | KLH conjugated synthetic peptide derived from human CD163. Please contact us for the exact immunogen sequence. The peptide is available as orb374759. |
| Target | CD163 |
| Alternative Names | (click to expand) |
| Form/Appearance | 10 mM PBS, 0.02% sodium azide |
|---|---|
| Concentration | - 100 μg (in 200 μl): 0.5 mg/ml |
| Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Purity | Polyclonal antibodies are purified by peptide affinity chromatography |
| MW | 125 kDa |
| Uniprot ID | |
| NCBI | NP_004235.41; NM_004244.51 |
| Entrez | 9332 |
Rabbit polyclonal antibody to CD163. This protein (also known as M130), belongs to a macrophage-associated antigen, which is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. CD163 acts as a receptor that scavenges hemoglobin by mediating endocytosis of haptoglobin-hemoglobin complexes.
| Dilution Range | IHC-P: 1: 100-600, WB: 1:500, ICC: 1:100 |
|---|
1. de Vries, M.et al. Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels J. Intern. Med. , (2018)
2. Koronyo, Y.et al. Therapeutic effects of glatiramer acetate and grafted CD115? monocytes in a mouse model of Alzheimer's disease Brain 138, 2399-2422 (2015)
3. Mertens, B.et al. Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice Oncotarget 9, 21978-22000 (2018)
4. Chen-Roetling, J.et al. Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin J. Neurochem. 139, 586-595 (2016)
5. Gibson, D.et al. Maternal exposure to fish oil primes offspring to harbor intestinal pathobionts associated with altered immune cell balance Gut Microbes 6, 24-32 (2015)
6. Heindryckx, F.et al. Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse model Eur J Gastroenterol Hepatol 24, 1020-1032 (2012)
7. Koronyo-Hamaoui, M. et al. Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease. Brain, (2019)
