Astemizole

SKU: orb1309145

Description

Astemizole is a long-acting, non-sedative H1 receptor antagonist with minimal anticholinergic activity. It is used in research on allergic conditions like rhinitis and urticaria, and serves as a pharmacological tool in both in vitro binding assays and in vivo models of allergy and asthma.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 68844-77-9
• MW: 458.57
• Purity: 99.88% (May vary between batches)
• Formula: C₂₈H₃₁FN₄O
• SMILES: C(N1C=2C(N=C1NC3CCN(CCC4=CC=C(OC)C=C4)CC3)=CC=CC2)C5=CC=C(F)C=C5
• Target: Histamine Receptor,Potassium Channel
• Solubility: DMSO:55 mg/mL (119.94 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.9 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antihistamine drug, antipruritic, Astemizole, Inhibitor, hERG K+, Laridal, Histamine Receptor, Histaminos, HistamineReceptor, histamine H1-receptor, H1 receptor, inhibit, KcsA, Paralergin, Potassium Channel, R 43512, R-43512, R43512, PotassiumChannel

Compound Identifiers

PubChem CID

2247