Tecastemizole

SKU: orb1305250

Description

Tecastemizole (R 43512) is a selective H1 receptor antagonist and a primary metabolite of astemizole, exhibiting anti-inflammatory properties. It is utilized in pharmacological research to study histamine pathways and inflammation in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 75970-99-9
• MW: 324.4
• Purity: 99.70% (May vary between batches)
• Formula: C₁₉H₂₁FN₄
• SMILES: Fc1ccc(Cn2c(NC3CCNCC3)nc3ccccc23)cc1
• Target: Histamine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.17 mM);DMSO:60 mg/mL (184.96 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tecastemizole, R 43512, R43512, R-43512, T 1348, T1348, T-1348, inhibit, Norastemizole, Inhibitor, HistamineReceptor, Histamine Receptor, H1 receptor, anti-inflammatory, allergy

Compound Identifiers

PubChem CID

123618