Anti-AXL / UFO Reference Antibody (tilvestamab)

• Catalog Number: orb1818412
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human, Monkey
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Concentration: 1mg/ml
• Protein Sequence: AXL / UFO
• UniProt ID: P30530
• MW: 146.22
• Tested applications: ELISA, FC
• Antibody Type: Primary Antibody
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: Tyrosine-protein kinase receptor UFO, 2.7.10.1, AX
• Note: For research use only

The purity of Anti-AXL / UFO Reference Antibody (tilvestamab) is more than 95%, determined by SEC-HPLC.

Immobilized human Axl FC at 2 µg/mL can bind Anti-AXL / UFO Reference Antibody (tilvestamab), EC50=0.01542 µg/mL

Anti-AXL / UFO Reference Antibody (tilvestamab) P-AKT Test was evaluated using U251 cell. The max induction fold was approximately 1.43.

Anti-AXL / UFO Reference Antibody (tilvestamab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

The endocytosis ratio tilvestamab by U251 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 40% at antibody concentration of 1 nM.

Human AXL HEK293 cells were stained with Anti-AXL / UFO Reference Antibody (tilvestamab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC127=0.07318 µg/mL