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Z-Pro-Pro-aldehyde-dimethyl acetal
Catalog Number: orb2277375
| Catalog Number | orb2277375 |
|---|---|
| Category | Small Molecules |
| Description | Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2]. |
| CAS Number | 170116-63-9 |
| Purity | 98.00% |
| MW | 376.45 |
| SMILES | C(=O)(N1[C@H](C(OC)OC)CCC1)[C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2 |
| Formula | C20H28N2O5 |
| Biological Activity | Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance is underscored by its role in the modulation of cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
