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Z-Pro-Pro-aldehyde-dimethyl acetal

SKU: orb2277375

Description

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease.

Research Area

Metabolism Research, Protein Biochemistry

Images & Validation

Key Properties

CAS Number170116-63-9
MW376.45
FormulaC20H28N2O5
SMILESC(=O)(N1[C@H](C(OC)OC)CCC1)[C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2
TargetProlyl Endopeptidase (PREP)

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

Z-Pro-Pro-aldehyde-dimethyl acetal (orb2277375)

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