Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

• Catalog Number: orb1909205
• Category: Small Molecules
• Description: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].
• CAS Number: 2245697-84-9
• Purity: 98.00%
• MW: 542.97
• SMILES: Cl.O=C(NCCOCCOCCOCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
• Formula: C₂₃H₃₁ClN₄O₉
• Biological Activity: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. It is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.