Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

SKU: orb1909205

Description

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation.

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Key Properties

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CAS Number	2245697-84-9
MW	542.97
Formula	C₂₃H₃₁ClN₄O₉
SMILES	Cl.O=C(NCCOCCOCCOCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Target	Autophagy,Others,E3 Ligase Ligand-Linker Conjugate,Apoptosis

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Autophagy,Others,E3 Ligase Ligand-Linker Conjugate,Apoptosis

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