Human PCSK9

SKU: orb2993454

Description

Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9 is produced by our Mammalian expression system and the target gene encoding Gln31-Gln692 (Val474Ile, Gly670Glu) is expressed with a 6His tag at the C-terminus.

Key Properties

• Expression System: Human Cells
• Biological Origin: Human
• Biological Activity: BLI: Loaded Biotinylated Human LDL R-Avi-His(Cat#orb2994702) on SA Biosensor, can bind Human APCSK9-His(Cat#orb2993454) with an affinity constant of 0.64 uM as determined in BLI assay.
• Tag: C-6His
• Molecular Weight: Predicted: 13.77&58.2 KDa. Observed: 19&60 KDa, reducing conditions
• Expression Region: Gln31-Gln692 (Val474Ile, Gly670Glu)
• Purity: SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.. SEC-HPLC: Greater than 95% as determined by SEC-HPLC. (QC verified)
• Endotoxins: < 1 EU/µg as determined by LAL test.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
• Form/Appearance: Supplied as a 0.2 μm filtered solution of 20mM NaH2PO4, 150mM NaCl, 0.1M Arginine, 0.1M Glu, 0.01% Tween20, pH 7.4.
• Disclaimer: For research use only

Alternative Names

Proprotein Convertase Subtilisin/Kexin Type 9; Neural Apoptosis-Regulated Convertase 1; NARC-1; Proprotein Convertase 9; PC9; Subtilisin/Kexin-Like Protease PC9; PCSK9; NARC1

Quick Database Links

UniProt

Q8NBP7