Human IL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer Protein

SKU: orb2992970

Description

Recombinant HumanIL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer is produced by our Mammalian expression system and the target gene encoding Met1-Ser212&Leu23-Asn254&Met1-Asp239 is expressed with a human IgG1 Fc tag at the C-terminus.

Key Properties

• Expression System: Human Cells
• Biological Origin: Human
• Biological Activity: BLI: Loaded Recombinant Human IL-2 (C-6His)(Cat#orb3002442) on HIS1K Biosensor, can bind Recombinant Human IL-2 R beta&IL-2 R alpha&IL-2 R gamma Heterotrimer Protein (C-Fc) (Cat#orb2992970) with an affinity constant of 2.96 nM as determined in BLI assay. (Regularly tested)
• Tag: C-Fc-Hole&C-Fc-Knob
• Molecular Weight: Predicted: 51.4&75.7 KDa. Observed: 54-66&98-140 KDa, reducing conditions
• Expression Region: Ala27-Asp239&Glu22-Ser212&Leu23-Asn254
• Purity: SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
• Endotoxins: < 1 EU/µg as determined by LAL test.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
• Form/Appearance: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
• Disclaimer: For research use only

Alternative Names

IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Quick Database Links

UniProt

P14784, P01589, P31785