Phospho-RSK1 p90 (Ser380) Antibody

• Catalog Number: orb1733010
• Category: Antibodies
• Description: Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: IP, WB
• Reactivity: Hamster, Mouse
• Isotype: Rabbit IgG
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser380 of human RSK1 p90
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 83 kDa; Observed MW: 90 kDa
• Entrez: 6195
• UniProt ID: Q15418
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kin
• Note: For research use only
• Expiration Date: 12 months from date of receipt.