pan-KRAS degrader 1

SKU: orb2665077

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Description

Pan-KRAS degrader 1 (Compound 1) is a broad-spectrum KRAS degrader, exhibiting an inhibitory constant Ki value of 25 nM against KRASG12V as determined by surface plasmon resonance (SPR). Additionally, this compound demonstrates antitumor activity.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2937327-83-6
MW	450.56
Formula	C₂₂H₂₆N₈OS
SMILES	C[C@]1(C2=C(SC(N)=C2C#N)CCC1)C3=NC(=NO3)C4=NC(=NC=C4)N5[C@@H](C)CNCCC5
Target	Ras

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

168909406 ↗

Key Properties

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No computed properties available.

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