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Catalog Number | orb419960 |
---|---|
Category | Proteins |
Description | Recombinant of mouse Galectin-9 protein |
Tag | N-GST |
Form/Appearance | Supplied as a 0.2 um filtered solution of 20mMPB,1mMEDTA,5mMp-ME,5%Trehalose,400mMNacl,ph6.5. |
UniProt ID | O08573 |
Protein Sequence | Met1-Thr322 |
Source | E.coli |
Expression System | E. coli |
Expression Region | E. coli |
Endotoxins | Less than 0.1 ng/ug (1 EU/ug) |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Buffer/Preservatives | Supplied as a 0.2 μm filtered solution of 1M PBS, 15% glycerol,pH8.0. |
Alternative names | Galectin-9; Lgals9; Gal-9. Read more... |
Note | For research use only |
Application notes | Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1. |
Expiration Date | 6 months from date of receipt. |
Unconjugated | |
95% | |
21.0 kDa | |
Mouse TIM-3, His Tag (orb334930) is expressed from human 293 cells (HEK293). It contains AA Arg 20 - Arg 191 (Accession # AAL65156.1). |
Unconjugated | |
90% | |
45.8 kDa | |
Mouse TIM-3, Fc Tag (orb334929) is expressed from human 293 cells (HEK293). It contains AA Arg 20 - Arg 191 (Accession # AAL65156.1). |
ELISA, MS, SDS-PAGE, WB | |
Greater than 95% as determined by reducing SDS-PAGE. | |
E. coli |
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