KRAS G12D inhibitor 17

SKU: orb1982739

Description

KRAS G12D Inhibitor 17 (example 8), a quinazoline-linked (4R)-4-hydroxy-L-prolinamide compound, acts as a proteolysis targeting chimera (PROTAC), specifically inducing degradation of the G12D-mutation KRAS protein.

Images & Validation

−

Key Properties

−

CAS Number	2821793-99-9
MW	1117.3
Formula	C₆₀H₆₅FN₁₂O₇S
SMILES	[H][C@]12CN(c3nc(OC4CCOCC4)nc4c(OCc5ccc(cc5)-c5cn(nn5)[C@@H](C(C)C)C(=O)N5C[C@H](O)C[C@H]5C(=O)N[C@@H](CO)c5ccc(cc5)-c5scnc5C)c(c(cc34)C3CC3)-c3c(C)c(F)cc4[nH]ncc34)[C@]([H])(CN1)C2
Target	Others,PROTACs,Kras,Ras

Storage & Handling

−

Storage	-20°C
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

Others,PROTACs,Kras,Ras

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols