JMV 449

SKU: orb1983808

Description

Potent, metabolically stable neurotensin receptor agonist peptide (IC50 = 0.15 nM for inhibition of [125I]-NT binding to neonatal mouse brain; EC50 = 1.9 nM for contraction of guinea pig ileum). Produces long-lasting hypothermic, neuroprotective and analgesic effects in mice following central administration in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 139026-66-7
• MW: 746.96
• Formula: C₃₈H₆₆N₈O₇
• SMILES: C([C@@H](NC[C@H](CCCCN)N)CCCCN)(=O)N1[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)[C@H](CC)C)=O)=O)CCC1
• Target: Neurotensin Receptor

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164415