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JBI-589

SKU: orb2278219

Description

JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors.

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Key Properties

CAS Number2308504-22-3
MW481.56
FormulaC29H28FN5O
SMILESC(N1C(=CC=2C1=CC=CC2)C3=C(C)N4C(=N3)C=C(C(=O)N5C[C@H](N)CCC5)C=C4)C6=CC=C(F)C=C6
TargetOthers

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

JBI-589 (orb2278219)

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