SARS-CoV-2 (COVID-19) S1 Protein, mFc Tag

SKU: orb640170

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Description

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Images & Validation

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Application Notes	This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 101.9 kDa. The protein migrates as 115-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	Spike S1
Reactivity	Virus
Tag	C-mFc(mIgG2a)
Molecular Weight	101.9 kDa
Expression Region	Val 16 - Arg 685
Purity	90%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Disclaimer	For research use only

SARS-CoV-2 (2019-nCoV) S1 protein NTD, mFc Tag [orb689471]

Purity:	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 59.1 kDa after removal of the signal peptide.The apparent molecular mass of S1-NTD-mFc is approximately 70-100 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 100 μg, 10 μg, 50 μg

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Recombinant SARS-Cov-2 Spike RBD protein, C-mFc (HEK293) [orb1516566]
Purity:
>95% as determined by Tris-Bis PAGE; >95% as determined by SEC-HPLC
MW:
65 kDa
Sizes Available: 100 μg, 500 μg
SARS-CoV-2 (COVID-19) S Protein RBD, mFc Tag [orb640173]
Conjugation:
Unconjugated
Purity:
95%
MW:
52.0 kDa
Sizes Available: 1 mg, 100 μg

Recombinant COVID-19/SARS-CoV-2 Spike RBD protein, mFc Tag [orb1141464]

Applications:	ELISA, WB
Purity:	≥95% as determined by SDS-PAGE
Source:	A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) Spike Protein (RBD) (YP_009724390.1) was fused a mFc tag at N terminus was expressed from Mammalian cells can bind with ACE2.

Sizes Available: 100 μg, 1 mg

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SARS-CoV-2 (COVID-19) S1 Protein, mFc Tag

Line graph illustrates about the Ag-Ab reactions using different concentrations of antigen and serial dilutions of of SARS-CoV-2 (COVID-19) S1 protein.

SDS-page analysis of SARS-CoV-2 (COVID-19) S1 protein.

Flow cytometric analysis of Vero E6 cells using SARS-CoV-2 (COVID-19) S1 protein.

SARS-CoV-2 (COVID-19) S1 protein.

Quick Database Links

Gene Symbol

Spike S1

UniProt

QHD43416.1

UniProt Details

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No UniProt data available

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