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| Catalog Number | orb623227 |
|---|---|
| Category | Proteins |
| Description | IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Human IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast. |
| Form/Appearance | Lyophilized |
| Protein Sequence | APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS (153) |
| MW | 17.4 kDa |
| Application notes | The Mouse IL-18 protein can be used in cell culture, as an IL-18 ELISA Standard, and as a Western Blot Control. |
| Source | Yeast |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 6 months from date of receipt. |
> 97% as determined by SDS-PAGE and HPLC. | |
17.3 kDa | |
E.Coli |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 43.5 kDa after removal of the signal peptide.The apparent molecular mass of IL1B-hFc is approximately 35-55 kDa due to glycosylation. | |
Mammalian |
> 97 % by SDS-PAGE and HPLC analyses. | |
Approximately 17.2 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids. | |
Escherichia coli |
> 97 % by SDS-PAGE and HPLC analyses. | |
Approximately 17.7kDa, a single non-glycosylated polypeptide chain containing 157 amino acids. | |
Escherichia coli |
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