Cryopyrin antibody

• Catalog Number: orb101128
• Category: Antibodies
• Description: Cryopyrin antibody
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IHC-P
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human Cryopyrin. Please contact us for the exact immunogen sequence. The peptide is available as orb374803.
• Concentration: - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
• Dilution range: IHC-P: 1:100-1:500
• Form/Appearance: 10 mM PBS, 0.02% sodium azide
• Purity: Polyclonal antibodies are purified by peptide affinity chromatography
• Conjugation: Unconjugated
• MW: 118 kDa
• Target: Cryopyrin
• Entrez: 114548
• UniProt ID: Q8R4B8, Q96P20
• NCBI: 001079821, 11, 21, 001073289
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti AGTAVPRL antibody, anti C1orf7 antibody, anti
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

He, Wei et al. Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model J Neuroinflammation, 16, 78 (2019)

PubMed: 30971286

Applications

IF, WB

Reactivity

Mouse

Wilson, C. Brad et al. Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder Behav Brain Res, 268, 72-80 (2014)

PubMed: 24675160

Applications

WB

Reactivity

Rat

He, Xue-Mei et al. Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia Oxid Med Cell Longev, 2020, 2963540 (2020)

PubMed: 33294118

Applications

IHC, WB

Reactivity

Rat and Mouse

Wilson, C. Brad et al. Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure animal model PLoS One, 8, e76146 (2013)

PubMed: 24130763

Applications

WB

Reactivity

Rat

Immunohistochemical staining of rat stomach tissue using Cryopyrin antibody (2.5ug/ml)

IHC-P staining of mouse testis tissue using anti-Cryopyrin (2.5ug/ml)

IHC-P image of rat colon tissue using anti-Cryopyrin (2.5ug/ml)

Immunohistochemical staining of paraffin embedded rat colon tissue using Cryopyrin antibody (2.5ug/ml)

Immunohistochemical staining of mouse lung tissue using Cryopyrin antibody (2.5ug/ml)