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Chroman 1

SKU: orb1308454

Description

Chroman 1

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1273579-40-0
MW436.5
Purity99.28%
FormulaC24H28N4O4
SMILESCOc1ccc2OC[C@H](Cc2c1)C(=O)Nc1ccc(cc1OCCN(C)C)-c1cn[nH]c1
TargetROCK
SolubilityDMSO:50 mg/mL (114.55 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (7.56 mM)

Bioactivity

Target IC50
MRCK:150 nM|ROCK1:52 pM|ROCK2:1 pM
In Vitro
Chroman 1 also shows inhibitory activities against MRCK IC50 150 nM). however, it has no effect on PKA IC50 > 20000 nM) or AKT1 IC50 > 20000 nM).

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

ROCK, ROCK1, ROK, ROCK2, Rho-kinase, rho kinase, Rho-associated protein kinase, Rho-associated kinase, spinal, inhibit, MRCK, glaucoma, injury, Inhibitor, cord, Chroman 1, Chroman1, Chroman-1

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Key Properties

No computed properties available.

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Protocol Information

Chroman 1 (orb1308454)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 220.00
1 ml x 10 mM (in DMSO)
$ 240.00
10 mg
$ 320.00
25 mg
$ 560.00
50 mg
$ 790.00
100 mg
$ 1,030.00
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