UK 227786

SKU: orb1819293

Description

UK 227786 is a selective phosphodiesterase 5 (PDE5) inhibitor utilized in research for prostatic conditions. It is applied in both in vitro and in vivo studies to investigate smooth muscle relaxation and lower urinary tract function.

Research Area

Metabolism Research

Key Properties

• CAS Number: 150452-21-4
• MW: 477.34
• Purity: >99.99% (May vary between batches)
• Formula: C₂₂H₂₂Cl₂N₄O₄
• SMILES: Cl.OC(=O)C1CCN(CC1)c1nc(NCc2ccc3OCOc3c2)c2cc(Cl)ccc2n1
• Target: PDE
• Solubility: DMSO:55 mg/mL (115.22 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1-[4-(1,3-Benzodioxol-5a-ylmethylamino)-6-chloroquinazolin-2-yl]piperidine-4-carboxylic acid, 1-[4-(1,3-Benzodioxol-5a-ylmethylamino)-6-chloroquinazolin-2-yl]piperidine-4-carboxylic acid;hydrochloride(150452-18-9 Free base), hydrochloride(150452-18-9 Free base), PDE5, UK227786, UK-227786, UK 227786

Compound Identifiers

PubChem CID

21183987