Tsugaric acid A

SKU: orb1297180

Description

Tsugaric acid A demonstrates protective effects against oxidative and UV-induced damage. It potently inhibits superoxide anion generation in stimulated neutrophils and shields human keratinocytes from UVB photodamage, making it a valuable compound for research in dermatology, photobiology, and inflammation.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 174391-64-1
• MW: 498.74
• Purity: 99.75% (May vary between batches)
• Formula: C₃₂H₅₀O₄
• SMILES: [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@@H](OC(C)=O)C(C)(C)[C@]1([H])CC3)[C@@H](CCC=C(C)C)C(O)=O
• Target: NO Synthase
• Solubility: DMSO:4.99 mg/mL (10.01 mM)

Bioactivity

• In Vitro:
  Twelve compounds, including ergosta-7,22-dien-3beta-ol (1), ergosta-7,22-dien-3beta-yl palmitate (2), ergosta-7,22-dien-3-one (3), ergosta-7,22-dien-2beta,3alpha,9alpha-triol (4), 5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol (5), ganoderal A (6), ganoderal B (7), ganoderic aldehyde A (8), Tsugaric acid A (9), 3-oxo-5alpha-lanosta-8,24-dien-21-oic acid (10), 3alpha-acetoxy-5alpha-lanosta-8,24-dien-21-oic acid ester beta-d-glucoside (11), and tsugaric acid B (12), were assessed in vitro by determining their inhibitory effects on the chemical mediators released from mast cells, neutrophils, and macrophages.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NO Synthase, inhibit, NOSynthase, Inhibitor, Tsugaric acid A

Compound Identifiers

PubChem CID

15292985