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R18

SKU: orb1679226

Description

This small molecule is a potent 14-3-3 protein antagonist (Kd ≈80 nM) that competitively disrupts 14-3-3 interactions with client proteins like Raf-1 and Bad, independent of ligand phosphorylation. It serves as a valuable chemical probe for studying 14-3-3 function in apoptosis and signal transduction pathways in both cellular and biochemical assays.

Research Area

Signal Transduction

Images & Validation

Key Properties

TargetRaf
Molecular Weight2309.69

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

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R18 (orb1679226)

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