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Catalog Number | orb1300855 |
---|---|
Category | Small Molecules |
Description | PHA-680632 |
CAS Number | 398493-79-3 |
Purity | 98.20% |
MW | 501.62 |
SMILES | CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1 |
Formula | C28H35N7O2 |
Biological Activity | PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |