PF-4693627

SKU: orb1706806

Description

PF-4693627 is a potent and selective microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with an IC50 of 3 nM. It is a valuable research tool for investigating inflammation pathways and has been utilized in preclinical studies for osteoarthritis and rheumatoid arthritis models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1312815-93-2
• MW: 502.43
• Formula: C₂₆H₂₉Cl₂N₃O₃
• SMILES: ClC=1C=C2C(OC(=N2)N3CCC(C(N[C@@H]4C[C@@H](CO)CCC4)=O)CC3)=CC1C5=CC=C(Cl)C=C5
• Target: PGE Synthase,Prostaglandin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53252516