Obafistat

SKU: orb1303507

Description

Obafistat is a highly potent and selective small molecule inhibitor of human aldo-keto reductase AKR1C3, exhibiting an IC50 of 1.2 nM. It is a valuable research tool for studying hormone-dependent cancers and other diseases in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2160582-57-8
• MW: 365.38
• Purity: 99.79% (May vary between batches)
• Formula: C₁₅H₁₆FN₅O₃S
• SMILES: Fc1cccc(c1)S(=O)(=O)N1C2CCC1CN(C2)C(=O)c1cnn[nH]1
• Target: NADPH,Others,Reductase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.47 mM);DMSO:62.5 mg/mL (171.05 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AKR1C3, inhibit, Obafistat, Inhibitor

Compound Identifiers

PubChem CID

132166612