Nithiamide

SKU: orb1309746

Description

Nithiamide (CL-5279) is an orally administered antiprotozoal compound used to treat vaginal trichomoniasis. It serves as a research tool for studying trichomonad infections, with applications in both in vitro antimicrobial assays and in vivo pharmacological research models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 140-40-9
• MW: 187.18
• Purity: >99.99% (May vary between batches)
• Formula: C₅H₅N₃O₃S
• SMILES: CC(=O)NC1=NC=C(S1)[N+]([O-])=O
• Target: Antibiotic,Antibacterial
• Solubility: DMSO:35 mg/mL (186.99 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.68 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vivo:
  For both sensitive and metronidazole-resistant strains of Trichomonas vaginalis, Nithiamide showed sustained potent activity under both aerobic and anaerobic conditions.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CL5279, CL-5279, CL 5279, Bacterial, Aminitrozole, Antibiotic, Inhibitor, Nithiamide, inhibit

Compound Identifiers

PubChem CID

8798