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NCT-502

SKU: orb1307976

Description

NCT-502

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1542213-00-2
MW395.45
Purity99.25%
FormulaC18H20F3N5S
SMILESCc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1
TargetDehydrogenase
SolubilityDMSO:55 mg/mL (139.08 mM);H2O:< 0.1 mg/mL (insoluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.06 mM)

Bioactivity

Target IC50
PHGDH:3.7 μM
In Vitro
NCT-502 is cytotoxic to MDA-MB-468 (EC50: 15.2 μM).

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide, NCT502, NCT-502, NCT 502, inhibit, PHGDH

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Key Properties

No computed properties available.

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Protocol Information

NCT-502 (orb1307976)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 100.00
5 mg
$ 100.00
10 mg
$ 120.00
25 mg
$ 210.00
50 mg
$ 300.00
100 mg
$ 480.00
500 mg
$ 1,030.00
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