JAK2/FLT3-IN-3

SKU: orb2663951

Description

JAK2/FLT3-IN-3 (11r) is a potent and selective dual inhibitor of FLT3 (IC50=0.51 nM) and JAK2 (IC50=2.01 nM). It demonstrates pro-apoptotic and anticancer activity in cellular assays, making it a useful chemical probe for researching hematological malignancies in vitro.

Key Properties

• CAS Number: 3038183-53-5
• MW: 611.78
• Formula: C₃₄H₄₅N₉O₂
• SMILES: O=C(NC1=CC=C(C=C1)C(=O)C)N2CCN(C3=NC(=NC=C3C)NC4=CC=C(C=C4)N5CCC(N6CCN(C)CC6)CC5)CC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171559344