Shogaol

• Catalog Number: orb1300192
• Category: Small Molecules
• Description: Shogaol
• CAS Number: 555-66-8
• Purity: 99.39%
• MW: 276.37
• SMILES: CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
• Formula: C₁₇H₂₄O₃
• Biological Activity: 1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.