[8]-Shogaol

SKU: orb1301796

Description

[8]-Shogaol, a bioactive constituent of ginger, acts as a selective cyclooxygenase-2 (COX-2) inhibitor, conferring its anti-inflammatory properties. It is utilized in research to investigate inflammatory pathways and has demonstrated activity in both cellular and animal models of inflammation.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 36700-45-5
• MW: 304.42
• Purity: 99.24% (May vary between batches)
• Formula: C₁₉H₂₈O₃
• SMILES: CCCCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
• Target: Apoptosis,COX
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (16.42 mM);DMSO:60 mg/mL (197.1 mM)

Bioactivity

• Target IC50:
  COX-2:17.5 μM (IC50)

Storage & Handling

• Storage: keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Apoptosis, 8-SHOGAOL, [8] Shogaol, [8]Shogaol, [8]-Shogaol, COX-2, COX, Cyclooxygenase

Compound Identifiers

PubChem CID

6442560