PL-017

SKU: orb1679392

Description

This compound is a potent and selective μ opioid receptor agonist, with an IC50 of 5.5 nM at μ sites and >10,000 nM at δ sites. In vivo, it induces analgesia, catalepsy, and hyperthermia in rats via central administration, effects which are reversible by naloxone. It is a valuable research tool for studying μ-opioid receptor pharmacology and neurobiology in both in vitro binding assays and in vivo behavioral models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: Opioid Receptor
• CAS Number: 83397-56-2
• MW: 535.64
• Formula: C₂₉H₃₇N₅O₅
• SMILES: C(N([C@H](C(=O)N1[C@@H](C(N)=O)CCC1)CC2=CC=CC=C2)C)(=O)[C@H]3N(C([C@H](CC4=CC=C(O)C=C4)N)=O)CCC3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

115335