NOTCH4 (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb67113
• Category: Antibodies
• Description: Rabbit polyclonal to NOTCH4.Neurogenic locus notch homolog protein 4 (NOTCH4) is a single pass membrane protein that belongsto the NOTCH family. NOTCH4 functions as a receptor for membrane-bound ligands Jagged1,Jagged2 and Delta1 to regulate cell-fate determination. NOTCH4 is cleaved upon ligand activationand the notch intracellular domain (NICD) is released, which forms a transcriptional activator complexwith RBPJ/RBPSUH to activate genes of the enhancer of split locus. It affects the implementation ofdifferentiation, proliferation and apoptotic programs.
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: C-terminal region of human NOTCH4
• UniProt ID: Q99466
• MW: 210
• Tested applications: WB
• Dilution range: WB:1:500-1:2000
• Storage: -20°C
• Alternative names: anti-NOTCH4 antibody,anti-Neurogenic locus notch h
• Note: For research use only

Western blot analysis of total cell extracts from human Jurkat using NOTCH4 antibody