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Nepicastat

SKU: orb1689394

Description

Nepicastat (SYN117) is a brain-penetrant, orally bioavailable inhibitor of dopamine-beta-hydroxylase (DBH), exhibiting potent activity against both bovine and human enzymes with IC50 values of 8.5 nM and 9 nM, respectively. This small molecule is a valuable research tool for investigating catecholamine regulation in preclinical models of cardiovascular and neuropsychiatric disorders.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number173997-05-2
MW295.35
FormulaC14H15F2N3S
SMILESC(N)C=1N([C@@H]2CC=3C(CC2)=C(F)C=C(F)C3)C(=S)NC1
TargetHydroxylase,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Nepicastat (orb1689394)

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