(R)-Nepicastat HCl

SKU: orb1686481

Description

(R)-Nepicastat HCl is the R-enantiomer of nepicastat and a potent, selective dopamine-β-hydroxylase inhibitor, exhibiting IC50 values of 25.1 nM (bovine) and 18.3 nM (human). It shows negligible activity against a broad panel of other enzymes and receptors. This selectivity makes it a valuable research tool for studying catecholamine regulation in cardiovascular and neurological disease models, both in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 195881-94-8
• MW: 331.81
• Formula: C₁₄H₁₅F₂N₃S·HCl
• SMILES: Cl.NCC1=CNC(=S)N1[C@@H]1CCC2=C(F)C=C(F)C=C2C1
• Target: Hydroxylase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

72163099