Hemipyocyanine

SKU: orb1705463

Description

Hemipyocyanine (CAS 528-71-2) is a virulence factor and α-amylase inhibitor produced by Pseudomonas aeruginosa. It is used in research to study bacterial pathogenesis and host-pathogen interactions, including investigations into its role in microbial competition and potential as an anti-infective target.

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 528-71-2
• MW: 196.2
• Purity: 99.75% (May vary between batches)
• Formula: C₁₂H₈N₂O
• SMILES: Oc1cccc2nc3ccccc3nc12
• Target: Amylase,Antibacterial
• Solubility: DMSO:60 mg/mL (305.81 mM)

Bioactivity

• In Vitro:
  The docking study indicated that HPC inhibits α-amylase by binding to amino acid Arg421 at the biding site on enzyme α-amylase with good binding energy (-9.3 kcal/mol) and creating two linkages of H-acceptors.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

528-71-2, Antibacterial, Hemipyocyanine, α-Amylase

Compound Identifiers

PubChem CID

135412648