FK-330

SKU: orb1697204

Description

FK-330 (FR-260330) is an orally bioavailable, selective inducible nitric oxide synthase (iNOS) inhibitor. It demonstrates potential anticancer activity and has been shown to protect against ischemia-reperfusion injury, as evidenced in a rat liver transplantation model. This small molecule is a valuable research tool for studying iNOS in oncology and transplantation research.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 442198-67-6
• MW: 617.02
• Purity: 99.95% (May vary between batches)
• Formula: C₂₉H₂₈ClF₃N₆O₄
• SMILES: [C@H](CC1=CC=CC=N1)(C(NCC(=O)N2CCC(OC=3C=C(C(F)(F)F)N=CN3)CC2)=O)NC(/C=C/C4=CC=C(Cl)C=C4)=O
• Target: NOS,NO Synthase
• Solubility: DMSO:50 mg/mL (81.03 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FR 260330, FR260330, FR-260330, FK330, FK-330, FK 330, NOS, LS 192510, LS192510, LS-192510

Compound Identifiers

PubChem CID

11308045