eFT508(Tomivosertib)

• Catalog Number: orb746346
• Category: Small Molecules
• Description: Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.
• CAS Number: [1849590-01-7]
• MW: 340.38
• SMILES: C1=NC(N)=CC(NC2C(=O)N3C4(CCCCC4)NC(=O)C3=C(C)C=2)=N1
• Formula: C₁₇H₂₀N₆O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.