Dacisteine

SKU: orb1308411

Description

Dacisteine (N,S-Diacetyl-L-cysteine) is a small molecule inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) with an IC50 of 1000 µM. It serves as a research tool for studying antibiotic resistance mechanisms and has been utilized in in vitro assays to investigate NDM-1 enzyme inhibition.

Research Area

Metabolism Research

Key Properties

• CAS Number: 18725-37-6
• MW: 205.23
• Purity: 99.71%
• Formula: C₇H₁₁NO₄S
• SMILES: CC(=O)N[C@@H](CSC(C)=O)C(O)=O
• Target: Others,Endogenous Metabolite
• Solubility: DMSO:250 mg/mL (1218.15 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (24.36 mM)

Bioactivity

• Target IC50:
  NDM1:1000 μM
• In Vivo:
  Dacisteine can be used for research on the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cerebrovascular, derivative, Endogenous Metabolite, disease, Cysteine, Dacisteine, cardiovascular, aggregation, inhibit, NDM-1, N,S-Diacetyl-L-cysteine, Inhibitor, platelet

Compound Identifiers

PubChem CID

65690