CDK12-IN-7

SKU: orb2564681

Description

CDK12-IN-7 is a potent dual inhibitor of CDK12 (IC50=42 nM) and CDK2 (IC50=196 nM). It demonstrates anti-proliferative activity in vitro, making it a useful chemical probe for oncology research, particularly in studying transcription regulation and cell cycle dynamics.

Research Area

Cell Biology

Key Properties

• CAS Number: 3033863-94-1
• MW: 663.65
• Formula: C₃₂H₃₂F₃N₉O₄
• SMILES: CN1C=2N(C=3C(N2)=NC(N(C(NCC4=CC=CC=C4)=O)[C@@H]5CC[C@@H](NC=6N=C(OC7COC7)C(C(F)(F)F)=CN6)CC5)=CC3)C=CC1=O
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171714343