AZ'3137

SKU: orb2664298

Description

AZ'3137 (Compound 22) is a potent, orally bioavailable PROTAC that degrades the androgen receptor (AR) with a DC50 of 22 nM. It demonstrates anti-proliferative activity in LNCaP cells (GI50 74 nM) and has shown efficacy in suppressing AR signaling and tumor growth in prostate cancer mouse models, supporting its use in oncology research.

Key Properties

• CAS Number: 2960179-55-7
• MW: 801.87
• Formula: C₄₃H₄₇F₄N₇O₄
• SMILES: N#CC1=CC=C(C(F)=C1C(F)(F)F)N2CCC(C3=CC=C(C=C3)N4CCC(CN5CCN(C6=CC(OC)=C7C(=O)N(CC7=C6)C8C(=O)NC(=O)CC8)CC5)CC4)CC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171922542