AnnH31

SKU: orb1701197

Description

AnnH31 is a potent and selective DYRK1A inhibitor (IC50 = 81 nM) with secondary activity against MAO-A (IC50 = 3.2 µM). It serves as a valuable chemical probe for investigating DYRK1A's role in cellular phosphorylation pathways, applicable in both in vitro enzymatic assays and cellular studies.

Research Area

Cell Biology, Metabolism Research, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 241809-12-1
• MW: 251.28
• Purity: 99.99%
• Formula: C₁₅H₁₃N₃O
• SMILES: C(C#N)N1C=2C(C=3C1=C(C)N=CC3)=CC=C(OC)C2
• Target: Monoamine Oxidase,MAO,DYRK
• Solubility: DMSO:50 mg/mL (198.98 mM)

Bioactivity

• Target IC50:
  Dyrk1A:81 nM|MAO-A:3.2 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DYRK1A, AnnH31, AnnH-31, MAO-A

Compound Identifiers

PubChem CID

9881447