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Research-Grade Biosimilar Antibodies

Advance your research with extensively characterized biosimilar antibodies. We deliver the analytical and functional validation required for reproducible in vitro and in vivo modeling.

>95% Monomeric Purity

Verified via lot-specific SEC-HPLC

Ultra-Low Endotoxin

In Vivo Grades guaranteed <0.1 EU/µg

Sequence Verified

Cloned from therapeutic innovators

★ The Validation Gold Standard

Featured Target: Amivantamab (orb2977888)

Amivantamab is a research-grade recombinant antibody targeting EGFR and c-Met. Produced in mammalian cells featuring native-like glycosylation, this biosimilar is suitable for PK/PD studies, assay development, and ADA research. This represents the high standard of purity and transparency applied across our catalog.

Human IgG1-kappa Mammalian Cells Unconjugated Purity >95% (SDS-PAGE)
Amivantamab Met Binding

Amivantamab Binding with Met

Detects recombinant human Met in indirect ELISA.

Amivantamab SDS Page Result

SDS-PAGE

>95% purity as determined by SDS-PAGE.

Top Biosimilar Targets

1-click access to highly characterized products matched to major clinical innovators.

View All Targets →

Amivantamab
EGFR / MET
Trastuzumab
HER2 / ERBB2
Omalizumab
IgE
Teplizumab
CD3
Adalimumab
TNF-alpha / TNFSF2
Infliximab
TNF-alpha / TNFSF2
Golimumab
TNF-alpha / TNFSF2
Etanercept
TNF / TNF receptor fusion
Nivolumab
PD-1 / PDCD1 / CD279
Varlilumab
CD27 / TNFRSF7
Pembrolizumab
PD-1 / PDCD1 / CD279
Cetuximab
EGFR
Rituximab
CD20 / MS4A1
Bevacizumab
VEGF-A / VEGFA
Landogrozumab
GDF-8

Procurement & Custom Support

Streamlined purchasing for preclinical trials with flexible sizing and dedicated technical assistance.

Flexible Quantities

Scale your research seamlessly. We offer available sizes ranging from 100µg for pilot studies up to gram-scale quantities for extensive in vivo trials.

Lot Reservation

Secure lot-to-lot consistency. We facilitate single-lot reservations and bulk orders to guarantee reproducibility across your entire project timeline.

Custom Technical Services

Need specialized isotypes, custom biomanufacturing, or specific assay formulations? For any other technical services, please reach out to our team.

Technical & Manufacturing FAQs

What exactly is a research-grade biosimilar?
A research-grade biosimilar is a recombinant antibody engineered to have the identical variable region sequence as a therapeutic drug. They are strictly for research use only (RUO) but are designed to behave identically to the commercial drug in preclinical models, ensuring consistent target engagement.
What are your quality control standards for biosimilars?
Every product undergoes rigorous lot-specific testing. We guarantee >95% monomeric purity as determined by SEC-HPLC and SDS-PAGE. For in vivo applications, our antibodies are tested using the LAL method to ensure ultra-low endotoxin levels (<0.1 EU/µg).
Can I request specific formats or custom isotypes?
Yes. To avoid unwanted immune responses or off-target effector functions (ADCC/CDC) in animal models, we can facilitate custom biomanufacturing. This includes providing mouse-matched chimeric backbones or specific Fc-silenced variants (like IgG4 S228P or LALA-PG). Please use our enquiry form for specialized requests.
What is the timeline for bulk orders and lot reservations?
For available catalog items, bulk quantities from 100µg up to 200mg can typically be dispatched within 5-6 weeks. We strongly recommend discussing your timeline with our procurement team to ensure seamless lot reservations for longitudinal studies.
Are these antibodies suitable for in vivo animal models?
Yes. Most of our biosimilars are suitable for In Vivo use and are formulated without carrier proteins or preservatives (BSA-free, Azide-free) and are tightly controlled for endotoxins, preventing unwanted systemic inflammation or immune responses in murine hosts. Check validated applications section on product page for more information.

Accelerate Your Preclinical Discovery

Partner with Biorbyt for reliable, extensively validated research-grade biosimilars designed to meet rigorous functional standards.

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