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TLR7/8 agonist 8
Catalog Number: orb1944362
Product Properties
| Catalog Number | orb1944362 |
|---|---|
| Category | Small Molecules |
| Description | TLR7/8 agonist 8 (compound 24m) is a potent dual agonist for toll-like receptors 7 and 8 (TLR7/8), exhibiting half-maximal effective concentrations (EC50s) of 27 nM for human TLR7 (hTLR7) and 12 nM for human TLR8 (hTLR8). This compound enhances the efficacy of PD-1/PD-L1 inhibitors in antitumor activity. |
| Target | Others |
| MW | 418.53 |
| CAS Number | 2649170-16-9 |
| Formula | C24H30N6O |
| SMILES | C(N1CC2(C1)COC2)C3=CC=C(CC4=NC5=C(C=C4)N=C(N)N=C5NCCCC)C=C3 |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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