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THR-β agonist 10

SKU: orb3173284

Description

THR-β agonist 10 is an orally active and selective THR-β agonist with an EC50 value of 11 nM. It effectively lowers levels of ALT (alanine aminotransferase), TC (total cholesterol), and LDL-C (low-density lipoprotein cholesterol). In mouse models of metabolic dysfunction-associated steatohepatitis (MASH), it improves steatosis, ballooning, inflammation, and fibrosis. THR-β agonist 10 is utilized in the research of MASH.

Images & Validation

Key Properties

TargetThyroid hormone receptor(THR)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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THR-β agonist 10 (orb3173284)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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