TAK-981

SKU: orb1218572

Description

TAK-981 is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities. (In Vitro):Subasumstat (TAK-981) is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, activating innate effector cells and enhancing the antitumor innate immune responses.(In Vivo):A single sub-cutaneous injection of Subasumstat (TAK-981) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs.

Key Properties

• CAS Number: 1858276-04-6
• MW: 578.1
• Purity: >98% (HPLC)
• Formula: C₂₅H₂₈ClN₅O₅S₂
• SMILES: Cc1c([C@@H]2NCCc(cc3)c2cc3Cl)cc(C(c2c(N[C@H](C[C@@H]3COS(N)(=O)=O)C[C@@H]3O)ncnc2)=O)s1
• Target: SUMOylation
• Solubility: DMSO:75 mg/mL (129.74 mM; Need ultrasonic)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Subasumstat

Quick Database Links

Gene Symbol

SUMOylation