Skatole

SKU: orb1301926

Description

Skatole (3-Methylindole) is a bacterially derived metabolite that acts as an aryl hydrocarbon receptor (AhR) agonist, activating pathways like p38 MAPK to modulate intestinal epithelial function. It is a valuable research tool for studying host-microbiome interactions, gut barrier integrity, and immune signaling in both in vitro and in vivo models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 83-34-1
• MW: 131.17
• Purity: 99.96% (May vary between batches)
• Formula: C₉H₉N
• SMILES: CC1=CNC2=CC=CC=C12
• Target: Antibacterial,Aryl Hydrocarbon Receptor,Antifungal,AhR,p38 MAPK,Apoptosis,Endogenous Metabolite,Autophagy
• Solubility: DMSO:50 mg/mL (381.18 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (15.25 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

p38 MAPK, p38MAPK, Skatole, Scatole, β-Methylindole, EndogenousMetabolite, Endogenous Metabolite, Fungal, Inhibitor, inhibit, Aryl Hydrocarbon Receptor, ArylHydrocarbonReceptor, Autophagy, Bacterial, b-Methylindole, beta-Methylindole, 3-Methyl-1H-indole, 3-Methylindole, 3-​Methylindole, AhR

Compound Identifiers

PubChem CID

6736