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SC-560

SKU: orb1223214

Description

SC-560 is a potent, orally active and selective inhibitor of COX-1. Using human recombinant enzymes, the IC50 value for SC-560 with respect to COX-1 is 9 nM, while the corresponding IC50 value for COX-2 is 6.3 μM.1 Thus, SC-560 shows 700-fold selectivity for the COX-1 enzyme.

Images & Validation

Key Properties

CAS Number188817-13-2
MW352.74
Purity>98% (HPLC)
FormulaC17H12ClF3N2O
SMILESCOc1ccc(cc1)n1c(cc(n1)C(F)(F)F)c1ccc(cc1)Cl
TargetCOX-1| COX-2
SolubilityDMSO : ≥ 100 mg/mL 283.49 mM; H2O : < 0.1 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SC-560 | SC 560 | SC560

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  • SC-560 [orb1303160]

    >99.99% (May vary between batches)

    188817-13-2

    352.74

    C17H12ClF3N2O

    5 mg, 25 mg
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Protocol Information

SC-560 (orb1223214)

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200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 150.00
25 mg
$ 290.00
50 mg
$ 350.00
100 mg
$ 440.00