S-Nitroso-N-acetyl-DL-penicillamine

SKU: orb1309139

Description

S-Nitroso-N-acetyl-DL-penicillamine

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 67776-06-1
• MW: 220.25
• Purity: 97.42% (May vary between batches)
• Formula: C₇H₁₂N₂O₄S
• SMILES: CC(=O)NC(C(O)=O)C(C)(C)SN=O
• Target: NO Synthase
• Solubility: DMSO:250 mg/mL (1135.07 mM);H2O:3.45 mg/mL (15.66 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (22.7 mM)

Bioactivity

• In Vitro:
  S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) induces approximately 80% toxicity under normoxic conditions by releasing nitric oxide (NO) after 6 hours . It has a half-life of about 6 hours in isolated rat ventricular myocytes and, at 100 μM for 30 minutes, causes a sustained decrease in basal pHi in these cells .

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NO Synthase, Nitric oxide synthases, inhibit, NOS, NOSynthase, Inhibitor, S Nitroso N acetyl DL penicillamine, SNAP, SNitrosoNacetylDLpenicillamine, S-Nitroso-N-acetyl-DL-penicillamine

Compound Identifiers

PubChem CID

5231